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recruiting a Post-doctoral Researcher for the study of the structure-function relationships of ribonucleic complexes during the translation initiation stage in higher eukaryotes. The project will consist in
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, nanostructuring, porosity) and their surface/interface physico-chemistry (functionalization, topography) in order to modulate or optimize their properties. The heterogeneous and complex structure of the studied
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such structured communities first emerge are still unclear. Also, how the current and past environmental characteristics affect host-associated microbiomes is unclear. The idea of this postdoc is to expand a
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. - Previous experience in one or more areas of chemoinformatics, drug design and structural biology of protein-ligand complexes. - Proficiency in tools and concepts related to molecular modelling (AlphaFold and
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reaction calculations. The candidate will then participate in a systematic assessment of the range of validity and limitations of this approach when moving toward heavier systems and more complex reaction
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. Using all-atom molecular dynamics simulations and enhanced sampling techniques, the project will investigate how S-glutathionylation modulates nucleosome structure and dynamics, alone and in combination
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the boundary layer and the turbines, but also at the center. This should shed some new light on the dissipative structures and extreme events possibly responsible for the large scale evolution of the flow
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language models to whole genome sequencing data - Develop algorithms and neural network architectures for the prediction of structured outputs (i.e. trees, graphs) - Implement and develop methods
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member of the Friedel-Jacquinot Federation, a physics coordination structure on the Moulon plateau in Orsay (IdF). It brings together around 100 researchers and teacher-researchers, experimentalists and
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, physical chemistry, photophysics and biology, and seeks to simultaneously extract structural, dynamical and environmental information at the single-molecule scale. Within the framework of this position