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17 Apr 2026 Job Information Organisation/Company CNRS Department Chimie des colloïdes, polymères et assemblages complexes Research Field Chemistry Physics » Chemical physics Physics » Biophysics
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between chemistry and biochemistry. It is structured around two parallel PhD projects: one in chemistry (the position offered) and one in biochemistry, supervised by partner research team. This organization
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of biologically relevant complex nucleosides requires a tedious, multi-step synthesis process. The proposed project aims to develop innovative metal-catalyzed C-H activation methods to access novel nucleoside
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, by integrating image analysis and docking across multiple structural states. The new tools will be validated through their application to VCP/p97 data, a key protein that plays a central role in
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Inria, the French national research institute for the digital sciences | Villers les Nancy, Lorraine | France | 14 days ago
complexes. The PhD will be carried out within the newly created Inria project-team DELTA at the Inria Center of the University of Lorraine, focusing on computational biology and artificial intelligence
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) datasets of VCP/p97 and VCP/97–ligand complexes. This will enable obtaining detailed maps of conformational states associated with mini-protein engagement, allowing assessment of how designed binders control
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PhD position: Nanoengineering refractory compositionally complex alloys for extreme conditions (M/F)
refractory compositionally complex alloys (RCCAs) in the form of thin films, targeting their application in extreme environments such as those encountered in nuclear fusion reactors. The approach relies
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for cryo-electron microscopy (cryo-EM) data analysis, modeling conformational heterogeneity, and identifying optimal binding candidates, by integrating image analysis and docking across multiple structural
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on the interplay between observations of natural phenomena, experimentation, and the modeling of the associated complex processes. ISTerre also conducts solid Earth observation missions, by hosting and
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advanced mesoscopic crystal plasticity provide powerful predictive capabilities, they remain computationally expensive when applied to realistic microstructures and large-scale structural analyses. A key