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. However, synaptopathy does not fully account for TTS-related hearing deficits. A complementary and promising hypothesis centers on the tip link6, a protein filament connecting adjacent stereocilia and
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in a living organism, especially when the damage occurs repeatedly over a lifespan. The central hypothesis of this PhD project is that repeated temporary threshold shifts interfere with tip link repair
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. The PhD (M/F), to be recruited in the context of the ERC StG MULTI-viewCELL, will be working on the development of a new method combining machine learning and biophysical modelling to model embryo
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