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of chromosomal mutations in bacteria; isolation of proteins expressed at native levels; proteomics and the analysis of proteomics data; high throughput genomic methods; the investigation of protein transport
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biology of cells is going from the equivalent of grainy black-and-white to high-resolution technicolor. From deciphering the choreography of transcription complexes, chromosomes, and RNA molecules within
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deciphering the choreography of transcription complexes, chromosomes, and RNA molecules within cells to developing novel approaches to 3D molecular structure determination to understanding how viruses hijack a
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of mammals inhabiting extreme terrestrial biomes. Planned projects combine state-of-the art sequencing methods to generate chromosome-level haplotype-resolved genomes and re-sequencing methods to address
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technicolor. From deciphering the choreography of transcription complexes, chromosomes, and RNA molecules within cells to developing novel approaches to 3D molecular structure determination to understanding how
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chromatin misregulation to replication dynamics, this project aims to uncover mechanisms that enable malignant cells to proliferate while preserving chromosomal integrity. Candidate Profile We seek candidates
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develop the foundational and scalable tools, technology and methods needed to synthesise large sections of human genomes/chromosomes. Through programmable synthesis of genetic material the aim is to unlock