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chromosome in Mycobacterium tuberculosis (Mtb), the pathogen causing Tuberculosis. In Mtb, chromosome dynamics are linked to several of the pathogen’s most distinctive and clinically problematic features
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chemical biology. Our mission is to understand and reprogram protein assemblies that control chromosome segregation and behavior. Applicants with expertise in structural biology or chemical biology are
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work package, as a Postdoctoral researcher in evolutionary genomics of sex chromosomes and sex-specific recombination in anurans andfor the validation of your doctoral research and, contains: A
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alterations in iPS cells. This project focuses on 8p syndrome, a developmental disorder caused by a complex rearrangement on chromosome 8p that results in neurodevelopmental delays, epilepsy, and other clinical
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chromosome 8p that results in neurodevelopmental delays, epilepsy, and other clinical features. Using our recently developed chromosome engineering approach, we have created isogenic stem cell lines that allow
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. The Marston lab investigates fundamental mechanisms of chromosome segregation in mitosis and meiosis. The successful candidate will work on a project to understanding the functional organisation of S. pombe
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chromosome replication. We work broadly across multiple themes in chromosome replication, including DNA replication termination, the role of accessory DNA helicases, how the MCM2-7 replicative helicase is
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, Bengaluru. The project will involve dissecting the mechanisms that regulate chromosome segregation and cell division using a range of structural biology, biochemical, and biophysical methods, complemented by
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recruiting for Postdoctoral Fellows: Leopold Parts – The Parts group works to engineer and model mammalian chromosomes. In particular, the group has long-term aims to delete, randomize, evolve, and model
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of gene dosage in regulating cellular function in male and female animals - from individual genes to chromosome-wide scales. We combine work in non-model organisms (like mosquitos or brine shrimp) with