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chemistry. A secondary duty is to co-supervise graduate students pursuing degrees in synthetic organic chemistry. The responsibilities include carrying out organic reactions aimed at achieving project goals
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understand the correlation between dengue vaccine protection and antibody enhancement. Unwanted/unsafe epitopes will be removed via viral engineering. Research skills in structural, engineering, and evolution
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of the underlying interactions. The approach uses a combination of conventional (rapid kinetics, protein engineering, X-ray crystallography) and innovative (smFRET, cryo-EM) biophysical techniques. Current projects
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the fundamental mechanisms of ion channels in excitable membranes using a multidisciplinary approach. Our NIH-funded research integrates structural biology, chemical biology, genetics, fluorescence microscopy, and