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, you will generate and study human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes and engineered cardiac tissues (ECTs). You will develop patient-specific cardiac models to identify
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mathematics, for example mapping out disease processes using single cell data, and using mathematics to simulate gigantic ash plumes after a volcanic eruption. In other words: there is plenty of room
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organism C. elegans to identify new mediators of this transcription stress response. These new mediators will subsequently be functionally characterized using genetic and cell biological analysis, in
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analyses (transcriptomics) and/or functional tests (cellular location, protein folding, enzyme activity, etc.). The work will involve close collaboration between clinicians, bioinformaticians, and molecular
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infections and vaccination strategies in farm and laboratory animals; design immunological study plans (e.g. T cell phenotyping, intracellular cytokine staining, immune correlates of protection) and translate
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candidate, you are at the core of the project. You will perform all wet lab analyses using advanced techniques such as cell culture, reporter analyses and RNA-sequencing. You will perform the data analysis
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: principal investigator dr. Lennart de Nooijer) at the Royal Netherlands Institute of Sea Research (NIOZ) is looking for a highly motivated PhD student with a background in cell biology/ (bio)geochemistry
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. These electrical impulses are generated in the muscle cells through the action of ion channels in the cell membrane, allowing entry and exit of charged ions. Variations in the genes encoding ion channels can cause
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of roots, nodules, and tubers, using reference genotypes and by manipulating abiotic factors (e.g. temperature, water, N). You will conduct molecular and cellular analyses using histology, microscopy, single
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Digital Twins: You will use numerical tools, including COMSOL and the open-source HemoCell simulation package, to model cell-scale thrombus formation. Experimental Validation: You will not just code; you