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iPSC-motor neurons derived from YARS1-CMT patients. Multimodal bioinformatics processing of the omics datasets will guide selection of differentially regulated key genes to be evaluated
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this, we will perform high resolution spatial transcriptomics and proteomics analyses in unique nerve biopsies and iPSC-motor neurons derived from YARS1-CMT patients. Multimodal bioinformatics processing
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sterile conditions) and familiarity with analytical techniques such as chromatography, microscopy, and with molecular biology methods. Bioinformatic expertise is not mandatory, but will be considered a plus
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