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of the experimental approach will include: Bayesian reconstruction of events on billion-year timescales, determination of optimal embeddings and encodings for protein structures, multiple structural alignments
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research with young children Experience with computational methods (e.g., Bayesian modeling, drift diffusion modeling, etc.) Equipment Utilized Physical Demands and Work Environment Overview Statement
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to: (i) identify novel metabolic vulnerabilities in KRAS-mutant lung cancer using in vivo and in vitro screening approaches; (ii) validate identified targets in vivo and elucidate the underlying mechanisms
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novel metabolic vulnerabilities in KRAS-mutant lung cancer using in vivo and in vitro screening approaches; (ii) validate identified targets in vivo and elucidate the underlying mechanisms; and (iii
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Associate will conduct genetic, microbiological, biochemical and animal studies to identify compounds that inhibit or kill Mycobacterium tuberculosis and to better understand their targets and mechanisms
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-targeting by ATPase enzymes in ribosome biogenesis. The main project involves studying the mechanisms of pre-ribosome maturation by motor proteins, an essential process for generating new ribosomes
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must be able to: Design and develop biochemical and cell-based assays for various drug targets. Perform high-throughput screening and structure-based drug design. Study the mechanism of action and