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Field
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investigating how bacteria repair protein–DNA crosslinks induced by fluoroquinolone antibiotics. The project, co-supervised by Prof Stephan Uphoff, aims to understand the molecular mechanism of the bacterial
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free of adventitious agents (AAs) such as bacterial and fungal contaminants. Current AA detection methods require lengthy culture times and are not suitable for continuous manufacturing, where rapid
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to understand the molecular mechanism of the bacterial exonuclease VII (Exo7) repair complex, which removes adducts of stalled type II topoisomerases from DNA and contributes to antibiotic tolerance
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following areas: A strong background in microbiology, including experience with bacterial and/or fungal culture, antibiotic susceptibility testing, rapid molecular detection of resistance genes or pathogens
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candidate will investigate the functions of bile metabolites induced by bacterial infection. We aim to advance our understanding of how infection-stimulated bile metabolites influence intestinal defense
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. Experience with bacterial cultures and aseptic technique. Experience with molecular approaches to study bacterial survival and antibiotic resistance. Preferred Qualifications: ● Experience with bacterial
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advanced measurement techniques to test these models in living cells. The detailed knowledge of bacterial physiology is combined with the sensitive measurement tools to develop innovative solutions
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. Experience with bacterial cultures and aseptic technique. Experience with molecular approaches to study bacterial survival and antibiotic resistance. Preferred Qualifications: ● Experience with bacterial
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of the human body, living for example in gut, on the eye and skin in the total number of dozens of trillions of cells. Estimates suggest there are more than ten thousand bacterial species living in
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field, with a strong record of experimental research and peer-reviewed publications. Required. Expertise in protein biochemistry, including recombinant protein expression and purification from bacterial