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Field
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will be Isolation of antigen-specific B cells and plasma cells from patient samples Generation of recombinant monoclonal antibodies Generation of B-cell receptor transduced cell lines Antibody-antigen
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response. The Postdoctoral Associate will be responsible for: Designing antibody panels to examine the bladder innate immune response during various challenges, including bacterial infection. Participating
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identification and mechanistic studies, in collaboration with researchers at Uppsala University Evaluation of promising drug candidates Mechanistic studies of antibody-mediated inflammation The position combines
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expression of a HIV-1 broadly neutralizing antibody (bNAb) in plasma for years without redosing. The systemic HIV-1 immunity achieved by this strategy could block acquisition of simian-HIV infection (SHIV) in
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and validate advanced methodologies for antibody characterization, such as ADE and ADCC assays, implement yeast-surface display for mapping antibody-antigen interactions, and establish systems
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antibody specificity profiling. KEY RESPONSIBILITIES You’ll join a small team advancing a new screening platform focused on therapeutic antibody specificity. The aim is to deploy this newly developed assay
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understand the correlation between dengue vaccine protection and antibody enhancement. Unwanted/unsafe epitopes will be removed via viral engineering. Research skills in structural, engineering, and evolution
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of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from
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parasite mutants, antibodies, spatial proteomics, real-time and super-resolution imaging, we will reveal essential protein domains and characteristics, will identify interacting protein partners and will
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XDP Sorter, Cytek Aurora and FACSAria II) for analysis and sorting of cells, and development of multicolor antibody staining panels. Experience in mouse handling, husbandry and dissection. Experience in