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Research Project Nucleic acids are potent triggers of immune responses. The presence of virus-derived RNA or DNA molecules activates nucleic acid sensors inside the host cell, which stimulates protective
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). These mutations do not always impair the enzymes’ canonical, ubiquitous functions but instead induce neomorphic activities, such as aberrant transcriptional regulation (Bervoets et al., Nature Communications 2019
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behavior and circuit integration remains poorly understood. In this project, you will develop and apply spatial transcriptomics methods and combine these with measurements of brain activity and cellular
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, and family situation. We welcome applications from individuals of all backgrounds and identities, and we are dedicated to providing equal opportunities and actively promoting a culture of belonging
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underlying brassinosteroid transport and its coupling with signalling, as well as the roles of phosphorylation in these processes and in the regulation of transporter activity and substrate specificity. We
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. Ultimately, the goal is to move towards an active-learning-based screening to unravel particular developmental and disease states in its entirety. The automated analysis of this data will be a key building
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at the cellular level, and (iii) applying quantitative image analysis to compare structural organization across fertile and infertile donors. The project is embedded in an active collaboration with a local