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. These coordinated hormonal activities influence not only the rate of cell division but also the duration and dynamics of each phase of the cell cycle. With the advent of advanced technologies, such as single-cell
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of the cell cycle. With the advent of advanced technologies, such as single-cell genomics and live-cell imaging, we can now explore hormone regulation at unprecedented single-cell resolution. Using these tools
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and Saeys teams. In this research project you will develop and apply algorithms to link clinical phenotypes of metastasis to molecular phenotypes in mouse models. It is known that metastases exhibit
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data. We have developed in vivo single-cell CRISPR technologies to screen for dozens of molecular factors in vivo during developmental and disease. These technologies are a game-changer in the speed