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Hepatology, Annals of Surgery , etc. Some of the key research topics in our laboratory include: Developing cell-free DNA (mutation and methylation) and RNA-based liquid biopsy biomarkers for cancer early
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combining interdisciplinary approaches with excellent tractability of the zebrafish heart to study a long-standing problem – how organ form and function emerge during development. Some of the fundamental
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drivers of advanced pediatric cancers and sarcomas to guide targeted therapy recommendations for individual patients and further develop precision medicine and immunotherapy for children with cancer
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areas of research include: Developing new multiplex assays to study effects of variants on diverse molecular processes, such as gene regulation and cell type differentiation Developing strategies
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RNA-Seq data. The position involves development of computational methods and pipelines for long read RNA-Seq data, and the analysis of transcript expression, alternative promoters and alternative
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health and the economy. The Research Group The Developmental Signalling Laboratory headed by Caroline Hill focuses on cell signalling in early vertebrate development and disease - see https
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on identifying the mechanisms of leukemogenesis and characterizing novel therapeutic targets in CEBPA mutant and inv(16) acute myeloid leukemia (AML). The lab has recently developed the first conditional knock-in
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regulation and other aspects of cellular signal transduction. We use our structural and mechanistic insights to drive development of novel anti-cancer drugs. Systems of current interest in the lab include RAF
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in normal intestinal homeostasis and perturbations that drive pathology, including risk for tumor development. Our research combines cutting-edge techniques, including single-cell RNA sequencing
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will need to tightly interact and collaborate with other postdocs and PhD students working on related aspects, having generated preliminary results and having developed essential perturbation and