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Advanced Grant (2025 – 2030). We have developed in vivo single-cell CRISPR technologies to screen for dozens of molecular factors in liver macrophages in vivo. We will apply these technologies to unravel
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in healthy states, genetically perturbed states, and during liver regeneration. On the other hand, you will develop algorithms to disentangle direct intercellular signals from those that are induced
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Saelens team. Research Project In this research project you will develop probabilistic deep-learning models that automatically extract biological and statistical knowledge from in vivo perturbational omics
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supported by a Foundation against Cancer (2025 – 2030). We have developed in vivo single-cell CRISPR technologies to screen for dozens of molecular factors in tumor-associated macrophages (TAMs) in vivo. We
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initiative investigating how human-specific features of brain development shape early behavior and neural circuit function in autism spectrum disorders (ASD). This position is a joint effort between the
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capacity at a three-fold increase. If the remaining liver is too small, the patient has high risk of developing the Small-For-Size Syndrome (SFSS), a post-operative failure causing death of one in three
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and Saeys teams. In this research project you will develop and apply algorithms to link clinical phenotypes of metastasis to molecular phenotypes in mouse models. It is known that metastases exhibit
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the Simons Foundation Autism Research Initiative (SFARI). This collaborative initiative with the labs of Pierre Vanderhaeghen (VIB-KU Leuven) and Franck Polleux (Columbia University) aims to elucidate how
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of the University of Antwerp and the Brussels Center for Immunology at the Vrije Universiteit Brussel. Description This project will investigate how peripheral immune signals shape brain and brain-border immunity and
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differentiation, shaping the overall course of plant development. Importantly, the synergy and interdependence of hormone signalling pathways are critical for driving cell cycle progression. These coordinated