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sources (ATP) and as secondary signaling molecules (cyclic dinucleotides). Synthetic analogues of nucleosides, nucleotides, and oligonucleotides represent a successful strategy to develop therapeutics
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methods to improve systems, and ML research develops such methods. Major gains are made when the development of ML and systems are symbiotic and co-optimized. This is relevant across a broad spectrum of
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clinicians as well as scientists from UKSHA, we have set up a unique facility to develop radiotracers (conjugating radiometals with different targeted molecules) and to evaluate them biologically in vitro and
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is a multidisciplinary research lab, providing the opportunity to develop extensive skills in a breadth of areas, including plant pathology, molecular biology, and computational biology. Whilst
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to alternative splicing. This PhD offers the scope to develop independence – pursing promising leads on interesting biology – while addressing one of evolution’s most longstanding challenges. Beyond advancing
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interactions (e.g. analytical ultracentrifugation and differential scanning fluorometry). Supported by personal and professional development programmes, the post holder will gain a wealth of transferrable skills
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this project will deliver unique knowledge to develop strategy aiming at enhancing root nodule symbiosis and, thus optimizing nitrogen nutrition, whilst ensuring long-term agricultural sustainability. To achieve
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that underpin immune recognition by these proteins, and how they could be engineered to expand or otherwise improve their use in agriculture. Our target for developing new disease resistance is the most
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(Beraza and Rushworth) whose work have a strong translational aim. This team will train the PhD student in a series of preclinical in vivo models; molecular biology and immunology methodologies; and complex
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. This iCASE studentship will provide a unique opportunity to join a collaborative research project between the Nicholson and Saunders Labs at JIC and develop skills in plant resistance mapping, wheat