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of natural products. The successful candidate will carry out the following duties: • Undertake the design and synthesis of a range of analogues of a natural product target as directed by Professor Chris Hayes
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. This programme of research will improve the diagnosis, treatment and prevention of respiratory disease through mechanistic discoveries that identify new drug targets and biomarkers, and that highlight drug re
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considerable utility as anti-inflammatory or anti-fibrotic treatments. However, drug discovery programmes targeting P2Y2 R have had limited success due to the low affinity and/or poor bioavailability
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applied in target synthesis of active pharmaceutical ingredients and the late-stage functionalisation of complex molecules. The successful candidate will carry out the following duties: • Undertake with
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a fundamental structural discovery programme targeting novel architectures and how to control structural transformations between them, in addition to exploring exciting new functional applications