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PhD candidate in Design and synthesis of pyrophosphate mimetics to study enzymes involved in natural
post-translational modification of proteins, with a confirmed role in various physiological processes such as DNA repair and antiviral defense. Protein targets are enzymatically modified with ADP-ribose
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, they introduce new and understudied attack surfaces. The research aims to uncover novel network-based threats targeting these systems and to develop robust countermeasures. By systematically identifying
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that it will target any DNA sequence. Not only does this make it possible to specifically target the DNA of a bacterial virus, but the method has also been found to be suitable for gene-editing in plants
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, allowing them to add to their existing clinical targets of anxiety and depression disorders, thus developing impact from this research. Methodology This studentship will take a mixed-methods approach to
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develop targeted antiviral therapies against specific viruses; on the other, we work on broad-spectrum pan-virus family antiviral agents. These broadly active compounds are essential for a rapid and
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strategies targeting R-loop-associated malignancies. See also https://www.imb.de/wang For a more detailed description of the project including relevant literature, see here[pdf-Datei] . This PhD position
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), leading to slow transfer times. Magdrive are developing the high-thrust SuperMagdrive propulsion system targeting 1N or higher thrust equivalent to the smallest chemical propulsion systems. Magdrive
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generated every day. By analysing this data in a targeted way and translating knowledge into action (from data to action), people can receive better – more effective and efficient – care and be better
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ultrasound. This project will develop the materials, methods, and designs necessary to 3D-print the next generation of medical micro-robots targeting drug delivery, exploiting combinations of functions
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of mesalazine in nanocarriers has demonstrated success in targeting inflammatory regions and treating mild to moderate IBD. This project will investigate the use of polymeric nanocarriers for improving