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analyses to patient-derived samples and disease models. Working closely with a dynamic and multidisciplinary team of clinicians and scientists, they will help generate and interpret high-resolution datasets
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have collated and curated the world’s largest publicly available dataset of M. tuberculosis samples with both genetic and drug susceptibility testing data. This data has many potential uses within
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, including PDX and in vivo models, and in vitro studies utilising primary patient samples. This role also includes you to supervise, train junior staff in epigenetic techniques and operate laboratory equipment
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. The research is primarily translational in nature, involving both preclinical models and human sample analysis from clinical trials, and is carried out in close collaboration with the pharmaceutical industry
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, to co-ordinate multiple aspects of work to meet deadlines. You will undertake laboratory work as required, such as sample preparation, cell culture, analysis of tumour samples and, tissue staining. Other
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, including murine in vivo models, as well as in vitro studies using primary in-vivo and patient samples. You will apply flow cytometry to monitor immune responses and utilize next-generation sequencing
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transwell culture systems, preparing samples for mass-spectrometry and RNA sequencing. Previous experience with complex in vitro culture systems, such as microfluidic chambers, is essential. It is also
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practical knowledge of protein purification, ensemble biochemistry, and sample preparation to support your biophysical studies; • interact with biochemist and structural biology collaborators based
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acquiring a practical knowledge of protein purification, ensemble biochemistry, and sample preparation to support your biophysical studies; • come up with suggestions to expand the interdisciplinary
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website . You will be required to submit a supporting statement, a CV, and a sample of your written work, published or unpublished, as part of your application. Note that the written work should be sent in