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, the challenge of understanding what dictates the structural differentiation of tau has remained unmet. Our group studies the formation of tau aggregates and more generally the molecular basis of tauopathies
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from the CNRS, the researcher will have to apply and develop a CSP (crystal structure prediction) methodology for the prediction and in silico design of materials. This could be based on generative
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“proof-of-concept” study as part of the “Larges échelles” structuring project, with the aim of publishing a scientific article on the natural (e.g. dams) and anthropogenic (dams and other structures
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); - Training a ML-based model using these simulation results; - AI-assisted topological optimization of lattices to improve overall performance. Additively manufactured “lattice” structures, composed of periodic
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of membrane protein structures through molecular dynamics • Characterization of conformational changes in transmembrane proteins associated with ligand binding and activation/deactivation • Virtual screening
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for elucidating the structure of insoluble or poorly soluble materials. This project aims to develop new high-resolution solid-state NMR strategies tailored for complex molecular systems, particularly
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cells can maintain calcium carbonate in a stable amorphous phase. One hypothesis is that the structure and/or chemistry of iACCs and their potential organic content could contribute to their stability. As
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will be conducted at the Institute of Molecular Microbiology and Structural Biochemistry of the Biosciences Campus of Lyon Gerland, next to the Infectious Diseases Research Center and the Jean Mérieux
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will be performed to determine the spatial distribution of the binder inside the pores. 1.2. Numerical Modeling: The candidate will develop a numerical model to reproduce the binder foam structure
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in Transylvania to study the genetic diversity structure of farm varieties (in situ). One of the key questions here will be to explore how the three human communities present in Transylvania structure