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Field
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of developmental biology using mass spectrometry imaging (MALDI-MSI). The candidate will focus on applying the insights of spatial molecular imaging using MALDI-MSI to define the molecular basis for development in
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single-cell or spatially resolved genomics methods Testing therapeutic interventions in models of ovarian and cardiovascular aging Designing in vivo lineage-tracing and labeling strategies paired with high
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spatial function) and alpha-synuclein (a protein that causes Parkinson’s disease and Dementia with Lewy Bodies) affect brain circuits. The postdoc’s work will encompass studies that are actively collecting
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genomic pathology approaches, including CRISPR, single cell sequencing, spatial transcriptomics, and image analysis to address biologically- and clinically-driven questions. Our overall aim is to
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of the intestines induced by radiation, with a focus on mechanisms of regenerative reprogramming. Complementary approaches will be used, including genetically engineered mouse models, histopathology, mouse and human
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | about 1 month ago
relapse, and metastatic progression. This work would involve a combination of ex vivo tumor-T cell co-culture assays, the use of in vivo tumor models, and the utilization of tumor clinical specimens
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computational modeling techniques to study planning in rodents engaged in dynamic spatial foraging tasks. The successful candidate will develop computational models of reinforcement learning in the brain and
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | about 9 hours ago
looking for a postdoctoral fellow interested in developing either machine learning algorithms for high-resolution histopathology imaging/spatial-profiling data in combination with other modalities (e.g
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. Specifically, the project will: Address a fundamental knowledge gap about how chromatin 3D organization determines transcription at a global scale in an explicitly defined neuronal development model. Integrate
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particular, the research project will focus on inferring trajectories from spatial transcriptomics data modelling at the same time the cells evolution in gene expression and in space. Required skills : We