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zebrafish and mouse lines Develop phenotypic rescue assays, based on selected readouts, in the generated disease models to test small molecule drug candidates Modern data management and precise project
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-class researchers from various fields, including neurophysiology, computational neuroscience, auditory cognition, genetics and genomics, cell biology and gene therapy. Most teams associate fundamental
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treatment strategies [14]. Recently, it was shown that it is possible to detect RNA modifications using long-read direct RNA sequencing by comparing an experimental test condition with a control condition
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proficient in programming languages commonly used in genomics research (e.g. Python or R) and have experience in working with bioinformatics software. Good knowledge of English is necessary. The successful
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based on the birthplaces of their grandparents and were genotyped (for ~9,700 of them) or sequenced (3,998 Illumina short read whole genome sequences 30X). The successful candidates will be responsible
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content near end-users. However, they still rely on a hierarchical and centralized network model. Peer-topeer systems like IPFS are the second class of candidates, but they lack robust guaranteesconcerning
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surveillance, random testing, wastewater, hospital surveillance) may help optimize epidemic monitoring, iii) modelling and comparing the patterns of spread of COVID-19, influenza and RSV by age group in France
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of the mouse colonies (genotyping and colony management using a dedicated software system). •Ensure quality and reproducibility of experimental results.•Keep up-to-date records of experimental works. •Meet
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Postdoctoral position: Developing a human lymphoid organ-on-chip to evaluate candidate mRNA vaccines
the assessment of responses to mRNA vaccines in the LO chip. The project will aim at further developing the LO chip platform, to better mimic lymphoid tissue organization and function. The candidate will test new
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. This will include implementing and applying software analysis pipelines and interpreting disease-related data together with experimental and clinical collaborators. Bioinformatics analyses guided by prior