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ribosome-mediated quality control and signaling pathways that govern cell fate decisions. The dysregulation of these surveillance mechanisms is linked to ribosome dysfunction, loss of proteostasis, and human
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lead to tissue failure and cancer, and to develop novel therapeutic approaches to mitigate and treat deleterious phenotypes that arise in patients with impaired DNA and RNA maintenance pathways. Some
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long-lasting protective immune memory and develop a therapeutic approach to treat chronic diseases. We have a strong interest in providing quality training to postdoctoral scholars and students, enabling
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disease. The primary focus of the lab is to elucidate how ribosomes act as sensors of cellular stress and to discover the ribosome-mediated quality control and signaling pathways that govern cell fate