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Technologies for Control and Signalling Systems (CIDET) – CZ.02.01.01/00/23_021/0008402) FACULTY: Faculty of Electrical Engineering and Informatics DEPARTMENT/INSTITUTE: Research Centre of the Faculty
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Dishevelled internal affairs in Wnt signaling Nucleic Acids Sensing Ribosome Assembly Mechanisms Deciphering the Argonaute Loading Mechanisms in RNA-Silencing Pathways More information about CEITEC PhD School
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, given that LAIR-1 is a negative regulator of immunoreceptor signaling in several immune cell types. In this project, we will test the hypothesis that increased expressions of LAIR-1 counterbalance
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Description Intramembrane proteases regulate a large number of important biological and pathophysiological processes, but the principles underlying their substrate recognition are still only rudimentarily
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focuses on the development of innovative human mammary organoids as an advanced in vitro model to investigate breast morphogenesis, a fundamental process in mammary gland development and a critical factor
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signals and transcription factor networks govern self-renewal, cell specification, differentiation, and reprogramming is a key step for advances in cell-based therapy and perspectives for medicine. Using
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the role of SRC-family kinases LCK and FYN in the T-cell antigen receptor signaling, which is crucial for proper T-cell development and immune response. It is known for decades that LCK, and to lesser extent
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tumorigenesis Characterization of cyclin-dependent kinase 12 (CDK12) substrates and their roles in regulation of transcription and tumorigenesis The mechanisms of signalling pathways deregulation in acute myeloid
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activating the druggable Jak/Stat3 signaling pathway. EMBO Rep 2022, e54729. [pubmed] [doi] Burocziova M, Grusanovic S, Vanickova K, Kosanovic S, Alberich-Jorda M: Chronic Inflammation Promotes Cancer
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., Quantum Espresso, VASP). Proficient written and oral communication skills in English. The ability to work independently and collaboratively. Admission Procedure: The admission process begins with