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The evolution of small-N systems School of Mathematical and Physical Sciences PhD Research Project Competition Funded UK Students Dr S Goodwin, Dr R Parker Application Deadline: 31 January 2026
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of rhizobial symbionts. The reasons for this, and the impact it has on rhizobial evolution are unclear. Many key questions remain outstanding, e.g. 'can symbiosis MGE transfer make anyone a symbiont?', 'what are
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acids institute (https://sheffield.ac.uk/nucleic-acids) and the centre for Single Molecule biology (https://smash.sites.sheffield.ac.uk/), providing additional expertise. This project will contribute
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training opportunities designed to support your career development, including communication and technology skills that are essential in academia, and industry. Visit http://www.sheffield.ac.uk/sgs to learn
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macropinosomes to retrieve membrane proteins and therefore sustain both immune and cancer cell function. Please apply for this project using this link: https://www.sheffield.ac.uk/postgraduate/phd/apply/applying
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of the science departments at the University of Sheffield, you’ll be part of the Science Graduate School. You’ll get access to training opportunities designed to support your career development by helping you gain
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Investigating how DNA damage responses combat infections by the typhoid pathogen Salmonella enterica
Srour et al. 2025, EMBO Mol Med (https://doi.org/10.1038/s44321-025-00347-8) ElGhazaly et al., 2023, Cell Reports (https://doi.org/10.1016/j.celrep.2023.113181) Ibler et al. 2023, Nat Commun (https
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transductions. Funding Notes Self-Funded Students only References https://sites.google.com/sheffield.ac.uk/peden-lab https://etheses.whiterose.ac.uk/28686/ View DetailsEmail EnquiryApply Online
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that the toxin induces DNA damage responses in cultured cells that activates a senescence tumour suppressor mechanism (https://doi.org/10.1038/s41467-019-12064-1). Cells undergoing toxin-induced senescence undergo
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to infinite-dimensional optimization problems that are often more challenging to solve. This project will focus on the continued development of a new type of direct transcription method named the integrated