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of the produced EVs using high resolution cell imaging. You will investigate the mechanism(s) of any EV-related chemotherapy resistance observed. Finally, you will attempt to target EV production (by CRISPR Cas9
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A search for pharmacological inhibitors of a cancer-associated adhesion GPCR in the zebrafish embryo
, chemoinformatics and image analysis). The student will gain experience in working with zebrafish embryos, and the use of high-content imaging techniques (fluorescent in situ hybridisation, immunohistochemistry
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administrative tasks, including creating requisitions where appropriate, goods receipting, and coding purchasing cards. Provide administrative support for recruitment activities, including job postings
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Work across multiple sites, including at Mettler Toledo Safeline X-ray and the University of Sheffield Carry out other duties, commensurate with the grade and remit of the post Person Specification Our
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proteomics approaches and a variety of imaging techniques, including high-throughput, confocal and live cell imaging. Please apply for this project using this link: https://www.sheffield.ac.uk/postgraduate/phd
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secretion from chromaffin cells. Using a combination of patch clamp electrophysiology and live cell fluorescent imaging the interactions between heterotrimeric G protein subunits, their effectors and the
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neurons. Using a combination of high resolution live cell fluorescent imaging, electrochemistry and patch clamp electrophysiology, we recently discovered that activation of GLP-1Rs promotes the formation
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for sustainable aviation fuels supply chain. The dual effects of sustainability and security of energy and critical materials supply will underpin the model development. It will involve a paradigm shift which
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. You will have diverse skill-set, good organisational skills, the ability to research, problem solve and implement ideas in a hands-on environment. Whilst having a practical approach, a positive attitude
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funding and industrial collaboration ensures the student will graduate with highly transferable skills, positioning them for a career in: Academia (postdoctoral research in universities and research