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closely related, these toxins act at different sites in the body owing to (a) differential binding to surface receptors, (b) internal trafficking and (c) differing final target substrates. It is well known
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at characterising the role of nutrient availability and of the ECM in promoting drug resistance and it’s composed of 3 objectives: - Characterisation of the effect of different nutrient starvation conditions and ECM
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shapes and morphologies of individual cells and their strategies for tissue-scale optimization. (2) Identifying interactions between different cell and tissue types, such as microglia, neurons, and blood
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-term time-lapse imaging to track different keratinocyte populations in zebrafish and high resolution Airy-Scan microscopy to understand cytoskeletal and cell adhesion changes. We will use advanced
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with the School Operations Team. Provide support for staff training days, including room booking and communicating information to relevant staff. In discussion with the Heads of Academic Unit, plan a
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. During your PhD you will use this system to identify the effects of different system parameters, part designs, and materials on temperature variability within the Laser Sintering process, and on
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differences in biodiversity over space and changes through time, and the relevance of these to conservation planning and management. Students will tackle specific questions regarding the distribution and
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advanced manufacturing methods to design graded materials with different properties in chemistry, biology, and biomechanics. Recent studies have highlighted the pivotal role of substrate stiffness in
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. Such projects will include understanding inter-specific differences in plant response, and how individual species responses drive ecosystem responses. Such studies may lead to determining the impacts
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will allow exploration of various forest configurations, including differences in tree density, species, and spatial distribution. Laboratory experiments will complement these models, using scaled-down