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of proteins or oligonucleotides exhibiting conformational flexibility is a major challenge for any experimental biophysical technique owing to a large number of degrees of freedom necessary, compared
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consequences. Currently, it is not possible to accurately predict the long term performance of a textile or fiber composite used for ballistic protection. Quantitative measurements of molecular structure
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on these materials is analogous to that on synthetic quartz half a century ago, with much to be determined about crystal growth, defect evolution, and dependence on crystallographic orientation before high-performance
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, such as selective labeling and contrast variation. Our second goal is to improve the accuracy with which solution scattering data of proteins and oligonucleotides can be predicted from the atomic
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applied to large biopharmaceutical products or platforms, and change the way scientists fundamentally deal with these types of data and biological systems. key words biotechnology; drug products; neutron
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@nist.gov 301.975.6740 Description With the development of nanoparticle and colloidal technologies that include processing in the dispersed phase (or are fundamentally liquid phase processes), there is a need
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Laboratory, Materials and Structural Systems Division opportunity location 50.73.11.C0581 Gaithersburg, MD NIST only participates in the February and August reviews. Advisers name email phone Li-Piin Sung
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of expansion and the completeness of differentiation is important to both efficient manufacturing and to product safety. Time-lapse microscopy of living cells allows the quantification of changes in dynamic
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product authenticity or adulteration. The goal of NIST’s ongoing effort with dietary supplements is to provide tools to the dietary supplement industry and measurement communities that will lead to improved
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scattering is routinely used to study solutions and surface adsorption of biomacromolecules. Neutrons are particularly well suited to study biological materials because of their sensitivity to light