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computational or mixed computational – experimental postdoc to use synthetic enhancers, CRISPR screening and computational approaches to unravel the logic of gene regulation in blood stem cell differentiation
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. The postholder will be responsible for the day-to-day maintenance and quality control of system performance, troubleshooting, and enhancing optical imaging systems, including widefield, confocal, multiphoton
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work will aid researchers in addressing an exciting question in gene regulation: how cells dynamically control the stability of messenger RNAs by selective degradation during protein synthesis by
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mutations disrupt a lead enhancer controlling a developmental enhancer cluster (Dev Cell, 2022). Human pancreatic islet 3D chromatin architecture provides insights into the genetics of type 2 diabetes (Nat
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transcriptional stabilizer of HNF1A (Nat Cell Biol 2022). Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster.(Dev Cell, 2022). Human pancreatic islet 3D chromatin
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, including asynchronous programming APIs: Experience developing and maintainingREST APIs • Advanced Linux knowledge • Proficiency with Git for version control • Hands-on experience with Docker