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in a highly translational research environment. Open access to CEITEC MU core facilities (https://www.ceitec.eu/core-facilities/ ) with state-of-the-art equipment and experienced staff members. Our
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after cultivation in vitro, and therefore it is necessary to use models of CLL microenvironment to culture CLL cells long-term and/or to study their proliferation. Several in vitro and in vivo models meet
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increased incidence of activated enhancer and promoter areas, allowing TFs to bind and subsequently aberrantly activate potential oncogenes. Moreover, specific post-translational modification of some TFs have
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sequencing from paired samples of FL and transformed FL and from FL samples before and after relapse. This pointed to several candidate non-coding RNAs that will be further studied. We will also integrate
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references: 1) A. Sasukimar et al. Supramolecular covalency of halogen bonds revealed by NMR contact shifts in paramagnetic cocrystals. Chem. Sci. 2025, 16, 20239-20244. https://doi.org/10.1039/D5SC05769H . 2
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-Guest Complementarity in Supramolecular Monofunctional Platinum(II) Drugs. Inorganic Chemistry Frontiers, 2024, 11, 8510-8525. https://doi.org/10.1039/D4QI02012J . Ideal candidate profile: Must-have