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Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt | Stein bei N rnberg, Bayern | Germany | 3 months ago
applications, improving lives. Recently, our Gene Editing group at the Institute of Stem Cell Research developed Synthetic Transfer Vehicles (STVs), a programmable protein-based RNA delivery platform
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gaps in our understanding of disease biology and treatment response in Black men. Our project aims to close these gaps by developing cutting-edge induced pluripotent stem cell (iPSC) models that better
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specialty in which the candidate's doctoral degree was conferred: PhD Tissue Engineering, Regenerative Medicine and Stem Cells, Biomaterials, Biology or related fields; b) Candidate's Curriculum Vitae
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., Alzheimer’s or Parkinson’s) and a track record of first author publications, a plus. Experience with the development and validation of advanced cellular models, such as induced pluripotent stem cell–derived
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to identify candidate disease-causing variants. You will develop model systems, e.g. genome-editing of immune or induced pluripotent stem cells (iPSC) with specific patient-derived genetic variants. We aim
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instability in human stem cells, disease, and cancer, using human pluripotent stem cells and targeted differentiation approaches as a primary working model. Our goal is to determine how DNA and RNA instability
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University of North Carolina at Chapel Hill | Chapel Hill, North Carolina | United States | 19 days ago
studies. The goals of the Rich Lab are to identify novel therapeutic paradigms in the treatment of advanced cancers, primarily malignant brain tumors, through the prism of stem cell biology to identify core
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Heidelberg). The work of our research group (http://lab.mueller-tidow.de ) focuses on stem cells and therapy resistance. We aim to understand how epigenetic dysregulation participates in the pathogenesis and
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mouse embryonic stem cells to allow for rapid protein depletion, mapping transcriptional effects (RNA-seq, TT-seq, PRO-seq), proximity labeling approaches, ChIP, and the bioinformatic analysis
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pursue independent projects during their training. The Barefield lab uses mouse models and human induced pluripotent stem cell derived cardiomyocyte models of genetic cardiovascular disease to study