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to stimuli, allowing them to transduce signals to the cell interior. Dynein-2 lies at the heart of these processes, as it is the molecular motor responsible for all retrograde transport from the tip of cilia
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. The project aims to elucidate the molecular mechanisms of dynein-2 transport in cilia using cutting-edge structural and biochemical approaches. Transport within cilia, the cell’s signalling and sensory antennae
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how Exo7 recognises and processes DNA-protein crosslinks and how this pathway contributes to bacterial survival following antibiotic treatment. This work will be tightly coordinated with live-cell
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, cutting-edge radio instrumentation and digital signal processing, citizen science, sky surveys, and studies of transient and variable objects. Listen is deeply involved with the department's educational
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cellular adhesion, inflammation, in addition to vital intracellular communication events such as epigenetics and signalling cascades. You must have (or be close to completion) a relevant PhD/DPhil in
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. The project involves developing and applying a novel integrated platform to study the chemical molecular mechanisms and signalling consequences of reactive small-molecule metabolites within important biological
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months. The project involves developing and applying a novel integrated platform to study the chemical molecular mechanisms and signalling consequences of reactive small-molecule metabolites within
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be determined by the funding available. About you You will hold or be near completion of a PhD/DPhil in Computational Biology, Bioinformatics, Genomics, or a closely related field, with significant
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. Candidates will be interviewed for both posts through a single interview process. The successful candidates will have their own distinct projects but should also be prepared to work closely with each other and
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starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available. About you You will hold a PhD/DPhil, or be near completion of a PhD