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biology, biochemistry, and cell biology techniques (e.g. molecular cloning, protein and RNA extraction, PCR, gel electrophoresis, western blotting, mammalian cell culture, genetic manipulation of cells
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have collated and curated the world’s largest publicly available dataset of M. tuberculosis samples with both genetic and drug susceptibility testing data. This data has many potential uses within
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approaches including targeted genetic murine models, primary cell culture and analysis, multi-omics and bioinformatics. The biological focus will be on vascular biology, immune cell function and metabolism
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in preventing immune-mediated pathology in autoimmunity remains poorly understood. Using genetic and antibody-based targeting, we aim to dissect how these pathways modulate T-cell signalling
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reverse genetics for generating recombinant influenza viruses, proximity labelling, and cross-linking mass spectrometry. The positions would suit enthusiastic and highly organised postdoctoral scientists
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induced by radiotherapy. You will employ a broad range of experimental approaches, including cell line engineering, transcriptional reporter assays, flow cytometry, qRT-PCR, ELISA, and CRISPR-based genetic
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areas in future. Based within the group of Dr Hugo Fernandes at the Department of Physiology, Anatomy and Genetics, you will be responsible for designing, validating, troubleshooting, and performing
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expertise in protein characterization, protein purification, and recombinant DNA techniques. Experience of working with membrane proteins, expertise in bacterial genetics, and expertise in quantitative