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vascular biology) alongside experience in cell biology and cell signalling in isolated primary cells. You must also have experience in phenotyping of genetically modified experimental models
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close to completion of a relevant PhD. You will manage your own academic research, effectively coordinating multiple strands of work. Direct experience in molecular genetics and/or plant-microbe interactions
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attached to the project. The successful applicant must hold a PhD/DPhil in a relevant subject. They must have peer-reviewed publications using data science approaches, for example, genetic analysis
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, genetic, and DNA methylation analyses to patient-derived samples and disease models. Working closely with a dynamic and multidisciplinary team of clinicians and scientists, they will help generate and
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myeloproliferative neoplasms (MPNs). You will take a lead role in conducting wet lab experimentation, applying state-of-the-art single-cell multiomic approaches, including transcriptomic, genetic, and DNA methylation
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biology, biochemistry, and cell biology techniques (e.g. molecular cloning, protein and RNA extraction, PCR, gel electrophoresis, western blotting, mammalian cell culture, genetic manipulation of cells
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), based at the Centre for Human Genetics, University of Oxford. The post aims to assist with the preparation and molecular characterisation of tumours using multi-omic analysis focusing principally
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approaches including targeted genetic murine models, primary cell culture and analysis, multi-omics and bioinformatics. The biological focus will be on vascular biology, immune cell function and metabolism
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on genetics, OMICs and other assays is essential. We are looking for a candidate who would be able to deliver high quality research outputs, as demonstrated by a strong publication record in high profile
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in preventing immune-mediated pathology in autoimmunity remains poorly understood. Using genetic and antibody-based targeting, we aim to dissect how these pathways modulate T-cell signalling