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of the lysosomal surface. Our goal is to reconstitute these signaling events in vitro to determine how physical changes in the membrane bilayer coordinate with biochemical signals to control cell fate. This work
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an integrative structural biology approach to understand how macromolecular structure and dynamics control function in systems relevant to infectious disease. We combine: Solution NMR spectroscopy (structure
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clinically indicated. Practices safety, environmental, and/or infection control methods. Coordinates the activities of patient care and support staff within the clinic. Work with the team to ensure smooth
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controllability • Learning and calibration strategies for uncertainty-aware language model prediction • Knowledge-augmented and neuro-symbolic approaches for language-based reasoning • Evaluation and design of LLM