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within the cortex region of a healthy adrenal gland. Quantifying the effect that pathway signalling dysregulation in different zones of the cortex has on expression levels of corticoids and androgens
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. About the PhD position : This project is part of Work Package 1: Hormone Dynamics within the ENDOTRAIN network. It aims to investigate how different replacement therapies affect immune function and
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of corticoids and androgens varies within the cortex region of a healthy adrenal gland. Quantifying the effect that pathway signalling dysregulation in different zones of the cortex has on expression levels
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different replacement therapies affect immune function and metabolism in patients with primary adrenal insufficiency. The project combines inflammation- and metabolism-related omics, dynamic hormone profiling
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different doses of hydrocortisone Integrate wearable-derived physiological data (e.g., BP, tissue glucose, activity, heart rate and sleep) with 24h dynamic hormone profiling, proteomics and patient-reported
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control study collecting wearable-based data and hormone profiles from healthy subjects (20) and PAI patients (20) at four different doses of hydrocortisone Integrate wearable-derived physiological data
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different streams. Apply for grant applications that lie in the center’s strategic interest and integrate research and advance the center’s research portfolio. Facilitate Knowledge Integration: Bridge work
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: Develop, lead and carry out research activities that cut across multiple research and innovation areas. Contribute to joint research outputs and innovation prototypes that integrate results from different
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multiple research and innovation areas. Contribute to joint research outputs and innovation prototypes that integrate results from different streams. Apply for grant applications that lie in the center’s