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PhD Studentship: Nanopore Technology for Rapid and Accurate Measurement of Antibiotic Concentrations
samples. Nanopore technology, which detects molecules via changes in ionic current as they pass through nanometer-scale pores, has revolutionised nucleic acid sequencing and holds untapped potential
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annually, with life-threatening consequences for immunocompromised individuals. With few antifungal drugs available and resistance on the rise, this project explores a novel strategy: engineering the fungal
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rather than the structured biofilms found in real-world environments. This project investigates how engineered surface topographies influence HGT dynamics, aiming to develop design principles for materials
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refer to the following website for eligibility criteria: https://www.ucl.ac.uk/prospective-students/graduate/research-degrees/physics-and-astronomy-mphil-phd . The studentship will cover university fees
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, translational insight, and valuable opportunities for career mentoring and networking with industrial and clinical experts. Desirable Prior Experience: Background in an aligned engineering or science discipline
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(SONATA, EP/V028626/1) and brings together expertise in microfluidics, fluid dynamics, nanoparticle engineering, and dental microbiology. Approach and Methods: Engineer in vitro models of bacterial biofilm
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for engineering novel antimicrobial peptides. The findings could lead to the development of new therapeutic scaffolds with applications in infectious disease, biotechnology, and immunotherapy. The project also
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). While mRNA vaccines have demonstrated rapid development and high efficacy, current formulations primarily protect against severe disease rather than preventing infection at mucosal entry points
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for microbiology and screening assays, MRC and Wellcome-funded. Both labs promote an open, collaborative culture and have a strong track record of PhD supervision. Desirable Prior Experience Some prior experience in
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/population genetics (van Dorp Lab) • Environmental microbiology, phage biology and metagenomics (Santini Lab) Both labs promote open research culture and have a strong track record of PhD supervision