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synthesis and formulation platforms, the project will generate and screen a diverse library of polymers optimised for mucosal delivery. The resulting delivery systems could enable next-generation vaccines
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About the Project A fully funded PhD scholarship is available at UCL Electronic & Electrical Engineering (4 years, home tuition fees covered, stipend provided). Exceptional international candidates
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Supervisors: Dr. Maximilian Besenhard Dr. Maryam Parhizkar Abstract: Antimicrobial peptides (AMPs) are natural molecules produced by the immune system and represent one of the most promising avenues
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challenging. This project aims to develop an ultrasound-assisted nanoparticle-based drug delivery system for targeted, controlled release of antimicrobials within these hard-to-reach oral microenvironments. By
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Supervisors: Dr. Duygu Dikicioglu Prof. Eli Keshavarz-Moore Abstract: Antifungal resistance is a growing and under-recognised global health threat. Fungal infections affect over a billion people
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The student will work across UCL Mechanical Engineering and RNOH, benefiting from a collaborative environment and access to state-of-the-art facilities. Research Environment: The project is hosted in
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Supervisors: Dr Darren N. Nesbeth Prof Eli Keshavarz-Moore Abstract: Horizontal gene transfer via conjugative plasmids is a major but underexploited driver of antimicrobial resistance (AMR) spread
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. Synthetic analogues will be developed and screened alone and in combination with existing antimicrobials. The ultimate goal is to design novel chemotherapeutic combinations that disrupt cell wall remodelling
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: Produce recombinant viral RNAP transcription complexes in insect cells Functionally characterise RNAP activity and validate assay systems Screen fragment libraries using fluorine-based NMR spectroscopy
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disinfectants. With antimicrobial resistance (AMR) on the rise, there is an urgent need for non-antibiotic strategies to prevent and control biofilm formation on medical devices. This PhD project proposes a novel