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, which aims to characterize bile duct inflammation in order to identify targetable molecular pathways using a range of multiomic techniques. In-depth characterization of animal models of bile duct
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contribute to a comprehensive understanding of gene regulation from DNA to proteins. Key scientific questions will include: How do 3D genome organization and enhancer-promoter spatial associations, as revealed
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and enhancer-promoter spatial associations, as revealed by Hi-C, inform transcription start site (TSS) usage? How does alternative promoter selection impact translation efficiency? The PhD is part of
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well as the mantle’s viscous response to the unloading of deglaciated ice. As a result, spatial differences in ice texture can locally enhance or slow down ice flow, leading to some areas with faster than average ice
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flow of ice from ice divides to the sea, as well as the mantle’s viscous response to the unloading of deglaciated ice. As a result, spatial differences in ice texture can locally enhance or slow down ice