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in healthy states, genetically perturbed states, and during liver regeneration. On the other hand, you will develop algorithms to disentangle direct intercellular signals from those that are induced
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and Saeys teams. In this research project you will develop and apply algorithms to link clinical phenotypes of metastasis to molecular phenotypes in mouse models. It is known that metastases exhibit
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Advanced Grant (2025 – 2030). We have developed in vivo single-cell CRISPR technologies to screen for dozens of molecular factors in liver macrophages in vivo. We will apply these technologies to unravel
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Saelens team. Research Project In this research project you will develop probabilistic deep-learning models that automatically extract biological and statistical knowledge from in vivo perturbational omics
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supported by a Foundation against Cancer (2025 – 2030). We have developed in vivo single-cell CRISPR technologies to screen for dozens of molecular factors in tumor-associated macrophages (TAMs) in vivo. We
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facilities and training in advanced techniques. Opportunities for career development, networking, and mentorship. Support for presenting at international conferences and publishing in peer-reviewed
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capacity at a three-fold increase. If the remaining liver is too small, the patient has high risk of developing the Small-For-Size Syndrome (SFSS), a post-operative failure causing death of one in three
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translational cancer research. Omics based strategies, such as (epi-)genomics and transcriptomics, are opening unprecedented potential for developing novel precision oncology tools for improved diagnosis
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adults, significantly impacting quality of life, and remain challenging to treat. Our research group has pioneered innovative methods to study voiding behavior in mice and developed live imaging techniques
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differentiation, shaping the overall course of plant development. Importantly, the synergy and interdependence of hormone signalling pathways are critical for driving cell cycle progression. These coordinated