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We provide gene targeting and mouse embryonic stem cell technology for members of the Rockefeller University, Memorial Sloan-Kettering Cancer Center and their collaborators. We continue developing and
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, working on projects that aim to develop and characterize the activity of engineered anti-inflammatory therapeutics, evaluating them in animal models of autoimmunity and chronic inflammatory diseases
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, working on projects that aim to develop and characterize novel, genetically engineered mouse strains, as well as in projects evaluating the mechanisms driving antitumor activity of immuno-oncology
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RNA is the driving force of biological complexity,determining which genes any given cell expresses at specific times and under specific circumstances. Darnell developed high-throughput sequencing and