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take a lead role in conducting wet lab experimentation, applying state-of-the-art single-cell multiomic approaches, including transcriptomic, genetic, and DNA methylation analyses to patient-derived
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myeloproliferative neoplasms (MPNs). You will take a lead role in conducting wet lab experimentation, applying state-of-the-art single-cell multiomic approaches, including transcriptomic, genetic, and DNA methylation
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the lab. This work will explore the molecular mechanisms of DNA damage responses and mutagenesis, and how sensitivity and resistance arise in different cancer cells and genetic backgrounds in response
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biology, biochemistry, and cell biology techniques (e.g. molecular cloning, protein and RNA extraction, PCR, gel electrophoresis, western blotting, mammalian cell culture, genetic manipulation of cells
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and Immigration website . Full-Time, Fixed-Term (36 months) We are looking for a highly motivated early career researcher with a PhD (or near completion) in psychology, life sciences, genetics
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have collated and curated the world’s largest publicly available dataset of M. tuberculosis samples with both genetic and drug susceptibility testing data. This data has many potential uses within
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approaches including targeted genetic murine models, primary cell culture and analysis, multi-omics and bioinformatics. The biological focus will be on vascular biology, immune cell function and metabolism
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be expected to lead the project with the supervisor and take responsibility for practical work including: molecular biology, C. elegans maintenance, genetics, and transgenics, live fluorescence
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in cancer and infection, their involvement in preventing immune-mediated pathology in autoimmunity remains poorly understood. Using genetic and antibody-based targeting, we aim to dissect how
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in preventing immune-mediated pathology in autoimmunity remains poorly understood. Using genetic and antibody-based targeting, we aim to dissect how these pathways modulate T-cell signalling