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The Department of biochemstry and biophysics. The National Facility for In Situ Sequencing (ISS), located at SciLifeLab in Solna, provides state-of-the-art ISS technology to researchers across
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Solna in Stockholm. In the Marklund lab (marklundlab.com ), we investigate how sequence information in biological macromolecules governs recognition, binding, and dynamical structure. We combine high
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systems, or network analysis. Experience with methods for causal inference, or modelling of biological systems is also considered a merit, along with prior work involving large-scale sequencing data such as
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cellular techniques, such as bulk and single-cell RNA sequencing, spatial transcriptomics, immunohistochemistry, immunoprecipitation, RNA-pull down, ChIP-seq, or CRISPR/Cas9-based gene editing etc. The exact
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. Experience with RNA sequencing (RNAseq) and associated analytical methods. Previous experience with evolutionary biology questions, particularly related to various bird models. Documented experience in
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the Karolinska Neuroimmunology and Multiple Sclerosis (KNIMS) division which gathers around 40 researchers working on different aspects of the pathogenesis of Multiple Sclerosis (MS) and other neurodegenerative
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bioinformatics, with a particular emphasis on performing analysis of high-dimensional data, which can be sequencing and/or imaging-based. Experience working with AI and machine learning approaches are considered a
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sequencing is performed routinely by multiple departments at the Karolinska hospital, including the clinical genetics department and the center for congenital metabolic diseases, totalling over 20 000 clinical
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bioinformatics, with a particular emphasis on performing analysis of high-dimensional data, which can be sequencing and/or imaging-based. Experience working with AI and machine learning approaches are considered a
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by using in vitro and in vivo models to recapitulate multiple steps of cancer metastatic events in real-time. Clinical samples from primary tumors and their metastatic descendants of the major cancer