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ranging between 15 and 30%. The necessity to find additional source of organs for transplantation has boosted research on the generation of organs from pluripotent stem cells (PSCs). We develop new
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-Calabuig et al., Cell Stem Cell 2023 ). Recently, we have developed EPI-Clone, a unique method to identify and characterize expanded stem cell clones independently of driver mutations and during
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. Unfortunately, around 50% of these individuals are unable to benefit from current or emerging treatments such as gene or stem cell therapies, pharmaceuticals, or retinal prostheses. Although cortical
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