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regulating stress and infection responses. Although it is known that all WRKY proteins interact with the same DNA motif, the mechanisms underlying their selectivity and the structure of WRKY–DNA complexes
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candidate will undertake a PhD project in experimental neurobiology at the interface of neuroscience and oncology, within the emerging field of Cancer Neuroscience. The research focuses on interactions
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at counteracting symptoms of brain disorders associated with astrocyte pathology. The applied research programme is designed to deliver a detailed understanding of the mechanisms of astrocyte dysfunction and its
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with—and drawing on the expertise of—Prof. Sobczak’s group, ASOs will be designed to target selected regulatory elements in order to reduce DMPK/CNBP expression or increase the expression of MBNL genes