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pluripotent stem cell (iPSC)-derived cultures and organoids. A key focus will be on understanding age-related cellular pathways and evaluating delivery nanoplatforms for RNA-based therapies across brain
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human induced pluripotent stem cell (hiPSC)-derived cardiomyocyte subtypes and autonomic neurons, as well as 3D tissues such as cardiac assembloids. The successful candidate will play a pivotal role in
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of functional glycans in situ and development of advanced infection model systems to study the role of functional receptors. These models will include (genetically engineered) stem cell-derived 2D and 3D
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systems including human induced pluripotent stem cell (hiPSC)-derived cardiomyocyte subtypes and autonomic neurons, as well as 3D cardiac assembloids. We seek a molecular engineer for a project aimed at
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stem-cell derived islets, offering patients better control of their blood glucose without insulin injections. In the Breakthrough T1D project, you will explore how smart drug delivery strategies can
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: To create hair-bearing skin constructs. Tasks You will determine necessary conditions for hair regeneration, apply hair follicle stem cells in skin constructs and subsequently explore the generation of hair
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of induced pluripotent stem cells (iPSC) of PD(D)/DLB patients to identify molecular profiles and drug targets. We will collect skin biopsies from PD patients of whom brain pathological confirmation is
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advanced human in vitro systems such as induced pluripotent stem cell (iPSC)-derived cultures and organoids. A key focus will be on understanding age-related cellular pathways and evaluating delivery
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living cells. Identify regulatory RNA switches involved in cell fate determination using both cancer cell lines and embryonic stem cell models of cell differentiation. Design and screen therapeutics