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tissues in the joint are affected. Recently, multiple OA risk genes were identified based on small genetic variations (SNPs) in the regulatory sequences of these genes. These variations can lead to
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at the edge of graphene” Disciplines: Nanophysics, Nanochemistry, Nanopore Sensing and Sequencing, Molecular Breakjunctions, Nanofabrication, Physical Chemistry, Organic Chemistry The research project DNA
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. While effective, such directed evolution campaigns are not only laborious and time-consuming, but also cover only a miniscule fraction of the unimaginably large sequence space available. As a result
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life sciences or biomedical sciences. You have hands-on experience in one or several of the following areas: organoids or embryo models, genome-wide approaches (sequencing-based, proteomics
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only laborious and time-consuming, but also cover only a miniscule fraction of the unimaginably large sequence space available. As a result, means to guide evolutionary trajectories along a biomolecule’s
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antinomy between rural areas (where food is produced) and cities (where food is consumed); by intervening in the sequence of spaces and buildings within the food chain with facilities open to
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for delta adaptation and development under uncertain changing conditions? How can we sequence measures that are made in different regions, e.g. using modelling tools? What is the timing of decisions and what
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measurement data for translating and testing model predictions; bioinformaticians, who investigate evolutionary conservation of sequence, (co)expression and regulatory modules; and modellers, who develop crop
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mechanisms by further exploring available post-mortem brain tissues and biofluids (blood and CSF) using various methods such as immunohistochemistry, incl. multiplex fluorescent imaging, RNA sequencing (bulk
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for translation and testing model predictions; bioinformaticians, investigating evolutionary conservation of sequence, (co)expression and regulatory modules; and modelers, developing crop-specific integrated plant