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Limitation:Temporary (3 years) Contract:TV-L Your tasks Infertility affects millions worldwide, yet in many cases the genetic basis remains unknown. Instead of focusing solely on gene-by-gene sequencing, this project
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regulate cancer cell plasticity in myeloid malignancies. Our overall goal is to pave the way for new cancer therapies. Inherited mutations in the RNA helicase DDX41 represent the most frequent genetic
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nanobelts. Your profile: We are looking for experimentally skilled candidates, ideally experienced in multiple-step organic synthesis Prior work on fused aromatic compounds is certainly advantageous
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candidates with a background in cell cycle regulation/mitosis and cell biology. The duration of mitosis is tightly regulated by multiple factors, including the spindle assembly checkpoint (SAC
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: From Mechanisms to Therapies”. In this CRC we aim to understand how plasticity i.e. non-genetic adaptations of the bone marrow niche induced by the disease or therapeutic agents contribute to drug
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& molecular analyses: Targeted microdissection of abnormal cells from Giemsa smears, extraction of DNA/RNA and molecular genetic analyses (e.g. targeted NGS, qPCR) to identify resistance genes and mutations