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advances in mass spectrometry now make it possible to detect proteins at true cytokine-level concentrations with high sensitivity and molecular specificity. Targeted proteomics, in particular, enables
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representations of results. Validate and consolidate identified targets through CRISPR-based perturbation assays, combined with transcriptomic and proteomic analyses in both human and murine models. Analyze
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of colorectal cancer (CRC) using organoid models. The researcher will focus on integrating dynamic mutations, live multiplexed transcriptomic imaging, and proteomic imaging at the cellular level to predict
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students. Several scientific platforms and facilities are available at the IBMC, including a proteomics platform, an insectarium, and a mouse animal facility. Other specialized equipment is also available
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(HCC). The project integrates whole-exome sequencing (WES), RNA sequencing, high-throughput serum proteomics (Olink), circulating tumor DNA analyses. The postdoctoral researcher will contribute primarily
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validated using high-throughput screening data, including microscopic images as well as genetic and proteomic expression data. This approach will then be applied to elucidate previously unknown gene functions
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OR DISCIPLINES1: Biological sciences JOB /OFFER DESCRIPTION The team « Membrane Proteomics and Cancer (MEMPROT)” at the Cancer Research Center of Marseille (CRCM) uses last advances in high resolution mass
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Network spanning 33 institutes worldwide. Host laboratory: The Mass Spectrometry for Biology Lab https://research.pasteur.fr/en/team/mass-spectrometry-for-biology/ )led by Julia Chamot-Rooke, is a dynamic
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throughout schizogony. For that we use cell and molecular biology, genetics, proteomics and advanced transcriptomics. We combine the strenghts of two different models: Plasmodium falciparum and Plasmodium
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), Eq3 (3D liver models), and Eq4 (Germany, redox chemistry, and proteomics). The objectives are to: - Develop a plasma jet to treat pathological liver tissue in situ, and analyze the physicochemical