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OXPHOS deficiency and the development of mitochondrial disease (MD). We will study the pathogenesis of MIP-linked mitochondrial disease by characterizing MIPs role in mammalian mitochondria. Additionally
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developed so far to more general geometric settings, including discontinuous coefficients, obstacles with Dirichlet or Neumann boundary conditions, and possibly manifolds. Details on the scientific project
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The project will be developed in the host laboratory(SIMHEL/U978) whose main pathophysiological models are two CD5+chronic B cell neoplasms (chronic lymphocytic leukemiaand mantle cell lymphoma
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mechanoelectrical feedback, it requires specific tools to uncouple them and to decode the transformation of complex acoustic stimuli by the brain. In the lab, we are developing electrophysiological and imaging
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The Machine Learning for Integrative Genomics team at Institut Pasteur, headed by Laura Cantini, works at the interface of machine learning and biology, developing innovative machine learning
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-mediated inflammation is a key early event in the development of tumor-associated inflammation—a hallmark of cancer that drives tumor growth and progression. AIM2 expression is notably elevated in lung
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focused on deep-phenotyping of individuals with autism and controls including brain imaging (MRI, fMRI, DTI and EEG) and a battery of cognitive tests. Our group is currently developing new methods
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insights into humoral immunity. This knowledge also informs the development of novel immunogens, vaccine strategies, and therapeutic antibodies with broad and potent activity to fight human infections
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-phenotyping of individuals with autism and controls including brain imaging (EEG and MRI) and a battery of cognitive tests. Our group is currently developing new methods for analyzing whole genome and brain